Firstly please read what type of tasks supercomputers can help you with and what type can not. If you decided to use MetaCentrum supercomputers you have to submit a registration form and sign a declaration about that you agree with the rules. Then the account on machines you apply for will be created. At the end of year you will be asked for a report about you computings in MetaCentrum and your accounts will be prolonged.
UNIX operating systems run into MetaCentrum machines. Machines are controlled remotely throught command line so you will need some program which stands for the terminal (at MS-Windows eg. Putty). Before submitting your job you have to log in a control server throught Telnet or SSH client which can encrypt the transmition. You also access to MetaCentrum machines throught login and password or throught Kerberos (you can find more about Kerberos authentication at: Kerberos page). In case of usage login and password you have to submit it every time you access from your machine to any MetaCentrum machine. In case you will utilize Kerberos you will get a ticket and then you can access to MetaCentrum machines without submitting password for 10 hours.
You log to cluster frontends, where you have an account, not to separate nodes. Use sone of cluster's frontends like skirit.ics.muni.cz, tarkil.cesnet.cz, konos.fav.zcu.cz, hermes.prf.jcu.cz or nympha.zcu.cz.
You have to copy input files to your home directory before submiting the job. To copy input/output files you can use SCP, FTP or RCP client for exapmple WinScp. You can see where your directories are placed on the page File systems.
Generally:
/afs/afs_cell/home/login/. This path can differ in various environments of particiapting companies. For example at UWB the path is /afs/afs_cell/users/first_login_letter/login//storage/home/login/ at NFSv4 on machines with feature nfs4. /home/login/ at NFSv3 (faster file network system for near systems)./scratch/login/ on every computational node for really fast temporary data storing .Please do not expect that home directory from machine skirit.ics.muni.cz (located in Brno) into which you move your data throught WinScp and into what you login throught PuTTY is availaible on clusters placed in Pilsen or Prague. You have to use AFS or NFSv4 directory for data sharing over all resources.
There are many machines and users in MetaCentrum so the computational jobs are run strictly throught batch system (PBSPro) that ensure effective and fair utilization of resources by users and plan when and why get requested machines.
Simply you don't run the task but insert it into batch system with requirements how much machines and how much processors with given properties and how big memory the task requires. Batch system assure that the task will be run as soon as possible. There is detailed tutorial to PBS but it is maybe to much detailed in some ways. It is better for beginner to continue to the page about applications running.